MTM1 Antikörper (AA 484-603)
Kurzübersicht für MTM1 Antikörper (AA 484-603) (ABIN7160627)
Target
Alle MTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 484-603
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Myotubularin protein (484-603AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MTM1 (Myotubularin 1 (MTM1))
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Andere Bezeichnung
- MTM1
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Hintergrund
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Background: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Aliases: AF073996 antibody, CG2 antibody, CNM antibody, KIAA4176 antibody, mKIAA4176 antibody, Mtm antibody, Mtm1 antibody, MTM1_HUMAN antibody, MTMX antibody, Myotubular myopathy 1 antibody, Myotubularin antibody, XLMTM antibody
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UniProt
- Q13496
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Pathways
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
Target
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