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MTM1 Antikörper (C-Term)

MTM1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263422
  • Target Alle MTM1 Antikörper anzeigen
    MTM1 (Myotubularin 1 (MTM1))
    Bindungsspezifität
    • 16
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 38
    • 32
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 36
    • 3
    • 1
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTM1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 15
    • 14
    • 13
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    MTM1 Antibody detects endogenous levels of total MTM1.
    Homologie
    Pig,Bovine,Horse,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MTM1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MTM1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MTM1 (Myotubularin 1 (MTM1))
    Andere Bezeichnung
    MTM1 (MTM1 Produkte)
    Synonyme
    CNM antikoerper, MTMX antikoerper, XLMTM antikoerper, wu:fb19c01 antikoerper, zgc:123266 antikoerper, myotubularin 1 antikoerper, myotubularin 1 S homeolog antikoerper, MTM1 antikoerper, mtm1 antikoerper, mtm1.S antikoerper, Mtm1 antikoerper
    Hintergrund

    Description: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

    Gene: MTM1

    Molekulargewicht
    70kDa
    Gen-ID
    4534
    UniProt
    Q13496
    Pathways
    Inositol Metabolic Process, Skeletal Muscle Fiber Development
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