MSH6 Antikörper
Kurzübersicht für MSH6 Antikörper (ABIN7160272)
Target
Alle MSH6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Kreuzreaktivität
- Human
-
Aufreinigung
- Protein G purified
-
Immunogen
- Recombinant Human MSH6 Protein
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Recommended dilution:IHC:1:50-1:500,
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
-
Andere Bezeichnung
- MSH6
-
Hintergrund
-
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.
Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein
-
UniProt
- P52701
-
Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
-