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MSH6 Antikörper

Dieses Anti-MSH6-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MSH6 in IHC und ELISA. Geeignet für Human.
Produktnummer ABIN7160272

Kurzübersicht für MSH6 Antikörper (ABIN7160272)

Target

Alle MSH6 Antikörper anzeigen
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Reaktivität

  • 142
  • 37
  • 30
  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 78
  • 61
  • 3
Maus

Klonalität

  • 94
  • 47
  • 1
Monoklonal

Konjugat

  • 62
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MSH6 Antikörper ist unkonjugiert

Applikation

  • 98
  • 79
  • 53
  • 51
  • 29
  • 18
  • 14
  • 13
  • 11
  • 11
  • 8
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA

Klon

2C12F3
  • Kreuzreaktivität

    Human

    Aufreinigung

    Protein G purified

    Immunogen

    Recombinant Human MSH6 Protein

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution:IHC:1:50-1:500,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    Andere Bezeichnung

    MSH6

    Hintergrund

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.

    Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein

    UniProt

    P52701

    Pathways

    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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