Midkine Antikörper (AA 21-143)

Produktnummer ABIN7159804

Dieses Anti-Midkine-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Midkine in IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für Midkine Antikörper (AA 21-143) (ABIN7159804)

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Midkine Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Midkine Antikörper

Bindungsspezifität: AA 21-143

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Midkine protein (21-143AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Midkine

Target: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Andere Bezeichnung: MDK

Hintergrund:

Background: Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development

Aliases: Amphiregulin associated protein antibody, Amphiregulin-associated protein antibody, ARAP antibody, FLJ27379 antibody, Mdk antibody, Midgestation and kidney protein antibody, Midkine antibody, MK 1 antibody, MK antibody, MK_HUMAN antibody, MK1 antibody, NEGF 2 antibody, NEGF2 antibody, Neurite growth promoting factor 2 antibody, Neurite outgrowth promoting protein antibody, Neurite outgrowth-promoting factor 2 antibody, Neurite outgrowth-promoting protein antibody, Retinoic acid inducible factor antibody

UniProt: P21741

Pathways: RTK Signalweg, M Phase, Skeletal Muscle Fiber Development