KDM1B Antikörper (AA 451-544) (Biotin)

Produktnummer ABIN7158729

Der Kaninchen Polyklonal Anti-KDM1B-Antikörper wurde für ELISA validiert. Er ist geeignet, KDM1B in Proben von Human zu detektieren.

Kurzübersicht für KDM1B Antikörper (AA 451-544) (Biotin) (ABIN7158729)

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM1B Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-KDM1B Antikörper (Biotin)

Bindungsspezifität: AA 451-544

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KDM1B

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Andere Bezeichnung: KDM1B

Hintergrund:

Background: Histone demethylase that demethylates \'Lys-4\' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \'Lys-4\' of histone H3. Has no effect on tri-methylated \'Lys-4\', mono-, di- or tri-methylated \'Lys-9\', mono-, di- or tri-methylated \'Lys-27\', mono-, di- or tri-methylated \'Lys-36\' of histone H3, or on mono-, di- or tri-methylated \'Lys-20\' of histone H4 (By similarity).

Aliases: amine oxidase (flavin containing) domain 1 antibody, amine oxidase, flavin containing 1 antibody, AOF1 antibody, bA204B7.3 antibody, C6orf193 antibody, dJ298J15.2 antibody, Flavin-containing amine oxidase domain-containing protein 1 antibody, FLJ33898 antibody, FLJ34109 antibody, FLJ43328 antibody, KDM1B antibody, KDM1B_HUMAN antibody, LSD2 antibody, lysine (K)-specific demethylase 1B antibody, Lysine-specific demethylase 2 antibody, Lysine-specific histone demethylase 1B antibody, Lysine-specific histone demethylase 2 antibody

UniProt: Q8NB78

Pathways: Warburg Effekt