KDM1B Antikörper (N-Term)

Produktnummer ABIN6972250

Der Kaninchen Polyklonal anti-KDM1B Antikörper (ABIN6972250) detektiert spezifisch KDM1B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für KDM1B Antikörper (N-Term) (ABIN6972250)

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KDM1B Antikörper

Bindungsspezifität: N-Term

Produktmerkmale: KDM1B / LSD2 (Lysine (K)-Specific Demethylase 1B / Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity). KDM1B / LSD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of mouse KDM1B / LSD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu KDM1B

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Andere Bezeichnung: KDM1B / LSD2

Molekulargewicht: 93 kDa

NCBI Accession: NP_758466

Pathways: Warburg Effekt