KDM1B Antikörper (Internal Region, N-Term)
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- Target Alle KDM1B Antikörper anzeigen
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
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Bindungsspezifität
- Internal Region, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM1B Antikörper ist unkonjugiert
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Applikation
- ELISA
- Kreuzreaktivität (Details)
- Cross reactivity with KDM1B from other species not tested.
- Aufreinigung
- Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
- Immunogen
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Immunogen: Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.
Immunogen Type: Peptide
- Top Product
- Discover our top product KDM1B Primärantikörper
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- Applikationshinweise
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Application Note: Anti-KDM1B Antibody is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user.
ELISA Dilution: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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0.01 % (w/v) Sodium Azide
Stabilizer: None
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- RT,4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
- Andere Bezeichnung
- KDM1B (KDM1B Produkte)
- Synonyme
- AOF1 antikoerper, C6orf193 antikoerper, LSD2 antikoerper, bA204B7.3 antikoerper, dJ298J15.2 antikoerper, 4632428N09Rik antikoerper, AI482520 antikoerper, Aof1 antikoerper, lysine demethylase 1B antikoerper, lysine-specific histone demethylase 1B antikoerper, lysine (K)-specific demethylase 1B antikoerper, KDM1B antikoerper, LOC577549 antikoerper, kdm1b antikoerper, Kdm1b antikoerper
- Hintergrund
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Synonyms: Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2
Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.
Gene Name: KDM1B
- Gen-ID
- 221656
- NCBI Accession
- NP_694587
- UniProt
- Q8NB78
- Pathways
- Warburg Effekt
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