LGR5 Antikörper (AA 241-352)

Produktnummer ABIN7158130

Dieses Anti-LGR5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LGR5 in IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für LGR5 Antikörper (AA 241-352) (ABIN7158130)

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGR5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-LGR5 Antikörper

Bindungsspezifität: AA 241-352

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 5 protein (241-352AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Andere Bezeichnung: LGR5

Hintergrund:

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.

Aliases: FEX antibody, G protein coupled receptor 49 antibody, G protein coupled receptor 67 antibody, g protein-coupled receptor fex antibody, G-protein coupled receptor 49 antibody, G-protein coupled receptor 67 antibody, G-protein coupled receptor HG38 antibody, GPCR GPR49 antibody, GPR 49 antibody, GPR 67 antibody, GPR49 antibody, GPR67 antibody, GRP 49 antibody, GRP49 antibody, HG 38 antibody, HG38 antibody, Leucine rich repeat containing G protein coupled receptor 5 antibody, Leucine-rich repeat-containing G-protein coupled receptor 5 antibody, LGR 5 antibody, LGR5 antibody, LGR5_HUMAN antibody, MGC117008 antibody, Orphan G protein coupled receptor HG38 antibody

UniProt: O75473

Pathways: WNT Signalweg