Rekombinanter LGR5 Antikörper
Kurzübersicht für Rekombinanter LGR5 Antikörper (ABIN7127600)
Target
Alle LGR5 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- LGR5 Recombinant Monoclonal Antibody
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human LGR5/GPR49
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Isotyp
- IgG
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibody
LGR5 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB14555 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 810-907) antibodyLGR5 Reaktivität: Human, Maus WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibodyLGR5 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2B5B9 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 Reaktivität: Human WB, FACS, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibodyLGR5 Reaktivität: Human, Maus WB, FACS, IHC, IF, IP Wirt: Maus Monoclonal 2A2 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibodyLGR5 Reaktivität: Human IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 605-638) antibodyLGR5 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB14210 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 238-270), (N-Term) antibodyLGR5 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB14764 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 349CT16-1-3-1 unconjugated
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Applikationshinweise
- WB:1:500-1:5000, FC:1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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Andere Bezeichnung
- LGR5
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Hintergrund
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Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
Aliases: Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38), LGR5, GPR49 GPR67
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UniProt
- O75473
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Pathways
- WNT Signalweg
Target
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