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IgD Antikörper (AA 1-240)

Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7156038
  • Target Alle IgD Antikörper anzeigen
    IgD
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 3
    • 1
    • 1
    AA 1-240
    Reaktivität
    • 43
    • 10
    Human
    Wirt
    • 25
    • 18
    • 9
    Kaninchen
    Klonalität
    • 30
    • 22
    Polyklonal
    Konjugat
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IgD Antikörper ist unkonjugiert
    Applikation
    • 21
    • 20
    • 13
    • 13
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ig delta chain C region protein (1-240AA)
    Isotyp
    IgG
    Top Product
    Discover our top product IgD Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IgD
    Andere Bezeichnung
    IGHD (IgD Produkte)
    Synonyme
    IgD antikoerper, Igh-5 antikoerper, immunoglobulin heavy constant delta antikoerper, immunoglobulin delta heavy chain constant region antikoerper, Ighd antikoerper, Igd antikoerper, IGHD antikoerper
    Substanzklasse
    Antibody
    Hintergrund

    Background: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.

    Aliases: IGHD antibody, Immunoglobulin heavy constant delta antibody, Ig delta chain C region antibody, Ig delta chain C region NIG-65 antibody, Ig delta chain C region WAH antibody

    UniProt
    P01880
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