HORMAD1 Antikörper (AA 201-394) (FITC)
Kurzübersicht für HORMAD1 Antikörper (AA 201-394) (FITC) (ABIN7155899)
Target
Alle HORMAD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-394
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human HORMA domain-containing protein 1 protein (201-394AA)
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Isotyp
- IgG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
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Andere Bezeichnung
- HORMAD1
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Hintergrund
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Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
Aliases: HORMAD1 antibody, NOHMA antibody, HORMA domain-containing protein 1 antibody, Cancer/testis antigen 46 antibody, CT46 antibody, Newborn ovary HORMA protein antibody
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UniProt
- Q86X24
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Pathways
- M Phase
Target
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