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HORMAD1 Antikörper (C-Term)

HORMAD1 Reaktivität: Human, Maus ELISA, WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262338
  • Target Alle HORMAD1 Antikörper anzeigen
    HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 32
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 30
    • 2
    Kaninchen
    Klonalität
    • 30
    • 2
    Polyklonal
    Konjugat
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HORMAD1 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 21
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    HORMAD1 Antibody detects endogenous levels of total HORMAD1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human HORMAD1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product HORMAD1 Primärantikörper
  • Applikationshinweise
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    HORMAD1 (HORMA Domain Containing 1 (HORMAD1))
    Andere Bezeichnung
    HORMAD1 (HORMAD1 Produkte)
    Synonyme
    CT46 antikoerper, NOHMA antikoerper, 4921522K05Rik antikoerper, Nohma antikoerper, RGD1564960 antikoerper, zgc:92129 antikoerper, HORMAD1 antikoerper, HORMA domain containing 1 antikoerper, HORMA domain containing 1 S homeolog antikoerper, HORMAD1 antikoerper, Hormad1 antikoerper, hormad1 antikoerper, hormad1.S antikoerper
    Hintergrund

    Description: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

    Gene: HORMAD1

    Molekulargewicht
    45kDa
    Gen-ID
    84072
    UniProt
    Q86X24
    Pathways
    M Phase
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