HORMAD1 Antikörper (AA 201-394)

Produktnummer ABIN7155897

Der Kaninchen Polyklonal Anti-HORMAD1-Antikörper wurde für ELISA validiert. Er ist geeignet, HORMAD1 in Proben von Human zu detektieren.

Kurzübersicht für HORMAD1 Antikörper (AA 201-394) (ABIN7155897)

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HORMAD1 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-HORMAD1 Antikörper

Bindungsspezifität: AA 201-394

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human HORMA domain-containing protein 1 protein (201-394AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HORMAD1

Target: HORMAD1 (HORMA Domain Containing 1 (HORMAD1))

Andere Bezeichnung: HORMAD1

Hintergrund:

Background: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

Aliases: HORMAD1 antibody, NOHMA antibody, HORMA domain-containing protein 1 antibody, Cancer/testis antigen 46 antibody, CT46 antibody, Newborn ovary HORMA protein antibody

UniProt: Q86X24

Pathways: M Phase