Retinoblastoma Binding Protein 4 Antikörper (AA 246-425)

Produktnummer ABIN7155453

Der Kaninchen Polyklonal Anti-Retinoblastoma Binding Protein 4-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Retinoblastoma Binding Protein 4 in Proben von Human zu detektieren.

Kurzübersicht für Retinoblastoma Binding Protein 4 Antikörper (AA 246-425) (ABIN7155453)

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Retinoblastoma Binding Protein 4 Antikörper

Bindungsspezifität: AA 246-425

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Histone-binding protein RBBP4 protein (246-425AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Andere Bezeichnung: RBBP4

Hintergrund:

Background: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.

Aliases: CAF I p48 antibody, CAF-1 subunit C antibody, CAF-I 48 kDa subunit antibody, CAF-I p48 antibody, Chromatin assembly factor 1 subunit C antibody, Chromatin assembly factor I p48 subunit antibody, Chromatin assembly factor/CAF 1 p48 subunit antibody, Histone-binding protein RBBP4 antibody, MSI1 protein homolog antibody, Nucleosome-remodeling factor subunit RBAP48 antibody, NURF55 antibody, RB binding protein 4 chromatin remodeling factor antibody, RbAp 48 antibody, RBAP48 antibody, RBBP-4 antibody, RBBP4 antibody, RBBP4_HUMAN antibody, Retinoblastoma binding protein 4 antibody, Retinoblastoma binding protein p48 antibody, Retinoblastoma-binding protein 4 antibody, Retinoblastoma-binding protein p48 antibody

UniProt: Q09028

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus