GCK Antikörper (AA 1-300)

Produktnummer ABIN7153890

Der Kaninchen Polyklonal Anti-GCK-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, GCK in Proben von Human zu detektieren.

Kurzübersicht für GCK Antikörper (AA 1-300) (ABIN7153890)

Target: GCK (Glucokinase (Hexokinase 4) (GCK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-GCK Antikörper

Bindungsspezifität: AA 1-300

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Glucokinase protein (1-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GCK

Target: GCK (Glucokinase (Hexokinase 4) (GCK))

Andere Bezeichnung: GCK

Hintergrund:

Background: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

Aliases: ATP:D-hexose 6-phosphotransferase antibody, FGQTL3 antibody, GCK antibody, GK antibody, GLK antibody, Glucokinase antibody, Hexokinase D pancreatic isozyme antibody, Hexokinase type IV antibody, Hexokinase-4 antibody, Hexokinase-D antibody, HHF3 antibody, HK IV antibody, HK4 antibody, HKIV antibody, HXK4_HUMAN antibody, HXKP antibody, LGLK antibody, MODY2 antibody

UniProt: P35557

Pathways: MAPK Signalweg, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process