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Cyclin D1 Antikörper (AA 1-295)

CCND1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN7153385

Datenblatt (PDF)

Target Alle Cyclin D1 (CCND1) Antikörper anzeigen

Cyclin D1 (CCND1)
Bindungsspezifität
20

16

16

14

12

9

9

8

7

6

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-295
Reaktivität
209

116

109

40

20

17

16

12

9

8

3

3

3

3

2

2

2

1

1

1

1
Human
Wirt
176

55

1
Kaninchen
Passende Sekundärantikörper
Klonalität
164

66
Polyklonal
Konjugat
118

21

17

7

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser Cyclin D1 Antikörper ist unkonjugiert
Applikation
184

73

62

61

39

30

28

27

24

20

20

12

6

5

3

2

2

2

1

1

1

1
ELISA

Kreuzreaktivität

Human

Aufreinigung

>95%, Protein G purified

Immunogen

Recombinant Human G1/S-specific cyclin-D1 protein (1-295AA)

Isotyp

IgG

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CCND1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D1 (CCND1) (AA 68-97) antibody
CCND1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB8066 unconjugated

anti-Cyclin D1 (CCND1) (AA 1-295) antibody
CCND1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 1F7F5 unconjugated

anti-Cyclin D1 (CCND1) (AA 167-295) antibody
CCND1 Reaktivität: Human ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 3B6G3 unconjugated

anti-Cyclin D1 (CCND1) (C-Term) antibody
CCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D1 (CCND1) antibody
KO Validated CCND1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated

anti-Cyclin D1 (CCND1) (C-Term) antibody
CCND1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D1 (CCND1) (AA 68-97) antibody
CCND1 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin D1 (CCND1) antibody
CCND1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal DCS-6 unconjugated

anti-Cyclin D1 (CCND1) (C-Term) antibody
CCND1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

Cyclin D1 (CCND1)

Andere Bezeichnung

CCND1 (CCND1 Produkte)

Hintergrund

Background: Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner
Aliases: AI327039 antibody, B cell CLL/lymphoma 1 antibody, B cell leukemia 1 antibody, B cell lymphoma 1 protein antibody, B-cell lymphoma 1 protein antibody, BCL 1 antibody, BCL-1 antibody, BCL-1 oncogene antibody, BCL1 antibody, BCL1 oncogene antibody, ccnd1 antibody, CCND1/FSTL3 fusion gene antibody, CCND1/FSTL3 fusion gene, included antibody, CCND1/IGHG1 fusion gene antibody, CCND1/IGHG1 fusion gene, included antibody, CCND1/IGLC1 fusion gene antibody, CCND1/IGLC1 fusion gene, included antibody, CCND1/PTH fusion gene antibody, CCND1/PTH fusion gene, included antibody, CCND1_HUMAN antibody, cD1 antibody, Cyl 1 antibody, D11S287E antibody, G1/S specific cyclin D1 antibody, G1/S-specific cyclin-D1 antibody, Parathyroid adenomatosis 1 antibody, PRAD1 antibody, PRAD1 oncogene antibody, U21B31 antibody

UniProt

P24385

Pathways

PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling