FANCD2 Antikörper (AA 1-291) (HRP)

Produktnummer ABIN7152551

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FANCD2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FANCD2 Antikörper (AA 1-291) (HRP) (ABIN7152551)

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCD2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-FANCD2 Antikörper (HRP)

Bindungsspezifität: AA 1-291

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Fanconi anemia group D2 protein (1-291AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Andere Bezeichnung: FANCD2

Hintergrund:

Background: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.

Aliases: DKFZp762A223 antibody, FA 4 antibody, FA D2 antibody, FA4 antibody, FAC D2 antibody, FACD 2 antibody, FACD antibody, FACD2 antibody, FACD2_HUMAN antibody, FAD antibody, FAD2 antibody, FANC D2 antibody, FANCD 2 antibody, FANCD antibody, FANCD2 antibody, FANCONI ANEMIA COMPLEMENTATION GROUP D antibody, Fanconi anemia complementation group D2 antibody, Fanconi anemia group D2 protein antibody, FANCONI PANCYTOPENIA TYPE 4 antibody, FLJ23826 antibody, OTTHUMP00000158853 antibody, OTTHUMP00000207925 antibody, Protein FACD2 antibody, Type 4 Fanconi pancytopenia antibody

UniProt: Q9BXW9

Pathways: DNA Reparatur