EDEM1 Antikörper (AA 46-128) (Biotin)
Kurzübersicht für EDEM1 Antikörper (AA 46-128) (Biotin) (ABIN7151971)
Target
Alle EDEM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 46-128
-
Kreuzreaktivität
- Human
-
Aufreinigung
- >95%, Protein G purified
-
Immunogen
- Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
-
Andere Bezeichnung
- EDEM1
-
Hintergrund
-
Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Aliases: EDEM1 antibody, EDEM antibody, KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody
-
UniProt
- Q92611
-
Pathways
- ER-Nucleus Signaling
Target
-