SMURF1 Antikörper (AA 198-374) (Biotin)

Produktnummer ABIN7151223

Produktdetails anti-SMURF1 Antikörper (Biotin)

Target: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Bindungsspezifität: AA 198-374

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMURF1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SMURF1

Target: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Andere Bezeichnung: SMURF1 (SMURF1 Produkte)

Synonyme: 4930431E10Rik antikoerper, mKIAA1625 antikoerper, RGD1309707 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 antikoerper, E3 ubiquitin-protein ligase SMURF1 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antikoerper, SMURF1 antikoerper, LOC100540915 antikoerper, smurf1 antikoerper, Smurf1 antikoerper, smurf1.L antikoerper

Hintergrund:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Aliases: E3 ubiquitin-protein ligase SMURF1 antibody, hSMURF1 antibody, KIAA1625 antibody, Smad specific E3 ubiquitin ligase 1 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, Smad ubiquitination regulatory factor 1 antibody, SMAD-specific E3 ubiquitin-protein ligase 1 antibody, SMUF1_HUMAN antibody, SMURF 1 antibody, smurf1 antibody

UniProt: Q9HCE7

Pathways: Regulation of Cell Size