SMURF1 Antikörper (AA 198-374) (Biotin)
Kurzübersicht für SMURF1 Antikörper (AA 198-374) (Biotin) (ABIN7151223)
Target
Alle SMURF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 198-374
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
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Andere Bezeichnung
- SMURF1
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Hintergrund
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Background: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Aliases: E3 ubiquitin-protein ligase SMURF1 antibody, hSMURF1 antibody, KIAA1625 antibody, Smad specific E3 ubiquitin ligase 1 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, Smad ubiquitination regulatory factor 1 antibody, SMAD-specific E3 ubiquitin-protein ligase 1 antibody, SMUF1_HUMAN antibody, SMURF 1 antibody, smurf1 antibody
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UniProt
- Q9HCE7
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Pathways
- Regulation of Cell Size
Target
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