MCM7 Antikörper (AA 360-719)

Produktnummer ABIN7150341

Der Kaninchen Polyklonal Anti-MCM7-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, MCM7 in Proben von Human zu detektieren.

Kurzübersicht für MCM7 Antikörper (AA 360-719) (ABIN7150341)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-MCM7 Antikörper

Bindungsspezifität: AA 360-719

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human DNA replication licensing factor MCM7 protein (360-719AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Andere Bezeichnung: MCM7

Hintergrund:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.

Aliases: CDABP0042 antibody, CDC 47 antibody, CDC47 antibody, CDC47 homolog antibody, Cdc47, S. cerevisiae, homolog of antibody, DNA replication licensing factor MCM7 antibody, Homolog of S. cerevisiae Cdc47 antibody, MCM 2 antibody, MCM 7 antibody, MCM2 antibody, MCM2, formerly antibody, Mcm7 antibody, MCM7 minichromosome maintenance deficient 7 antibody, MCM7_HUMAN antibody, Minichromosome Maintainence 7 antibody, Minichromosome maintainence, S. cerevisiae, homolog of antibody, Minichromosome maintenance complex component 7 antibody, Minichromosome maintenance deficient 7 antibody, Minichromosome maintenance protein 7 antibody, P1.1 MCM3 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS 146 antibody, PNAS146 antibody, PPP1R104 antibody, Protein phosphatase 1, regulatory subunit 104 antibody

UniProt: P33993

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA