POLK Antikörper (AA 227-337) (Biotin)

Produktnummer ABIN7150256

Produktdetails anti-POLK Antikörper (Biotin)

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Bindungsspezifität: AA 227-337

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLK Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA polymerase kappa protein (227-337AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLK

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Andere Bezeichnung: POLK (POLK Produkte)

Synonyme: DINB1 antikoerper, DINP antikoerper, POLQ antikoerper, Dinb1 antikoerper, POLK antikoerper, si:ch211-254o18.3 antikoerper, DNA polymerase kappa antikoerper, polymerase (DNA directed) kappa antikoerper, polymerase (DNA directed), kappa antikoerper, polymerase (DNA directed) kappa L homeolog antikoerper, POLK antikoerper, Polk antikoerper, polk antikoerper, Tb11.01.0080 antikoerper, Tb11.01.0010 antikoerper, Tb11.01.0020 antikoerper, Tb11.01.0030 antikoerper, Tb11.01.0040 antikoerper, Tb11.01.0050 antikoerper, Tb11.12.0001 antikoerper, Tb11.12.0002 antikoerper, Tb11.12.0003 antikoerper, polk.L antikoerper, polk-1 antikoerper

Hintergrund:

Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3\'-5\' proofreading exonuclease activity. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity.

Aliases: DinB homolog 1 (E. coli) antibody, DINB protein antibody, DINB1 antibody, DINP antibody, DNA damage inducible protein b antibody, DNA polymerase kappa antibody, Polk antibody, POLK_HUMAN antibody, POLQ antibody, Polymerase (DNA directed) kappa antibody, polymerase, DNA, kappa antibody

UniProt: Q9UBT6

Pathways: DNA Reparatur