CDK3 Antikörper (AA 220-297)
Kurzübersicht für CDK3 Antikörper (AA 220-297) (ABIN7148881)
Target
Alle CDK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-297
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
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Andere Bezeichnung
- CDK3
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Hintergrund
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Background: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Aliases: Cdk 3 antibody, Cdk3 antibody, CDK3_HUMAN antibody, CDKN3 antibody, Cell division kinase 3 antibody, Cell division protein kinase 3 antibody, Cyclin dependent kinase 3 antibody, Cyclin-dependent kinase 3 antibody, OTTHUMP00000206828 antibody, p36 antibody
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UniProt
- Q00526
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Pathways
- Zellzyklus
Target
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