Cyclin C Antikörper (AA 240-283) (FITC)

Produktnummer ABIN7148840

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin C in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cyclin C Antikörper (AA 240-283) (FITC) (ABIN7148840)

Target: Cyclin C (CCNC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin C Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-Cyclin C Antikörper (FITC)

Bindungsspezifität: AA 240-283

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-C protein (240-283AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Cyclin C

Target: Cyclin C (CCNC)

Andere Bezeichnung: CCNC

Hintergrund:

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody

UniProt: P24863

Pathways: Zellzyklus, Regulation of Lipid Metabolism by PPARalpha