COPS2 Antikörper (AA 1-310)
Kurzübersicht für COPS2 Antikörper (AA 1-310) (ABIN7148493)
Target
Alle COPS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-310
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human COP9 signalosome complex subunit 2 protein (1-310AA)
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Isotyp
- IgG
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anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 344-443) antibody
COPS2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4B12 unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyCOPS2 Reaktivität: Human, Maus WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-310) antibodyCOPS2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyVerified COPS2 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) antibodyCOPS2 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (Internal Region) antibodyCOPS2 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Kaninchen, Affe, Schwein, Huhn, Xenopus laevis, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-50) antibodyCOPS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Xenopus laevis WB, IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Kaninchen, Affe, Drosophila melanogaster, Schwein, Huhn, Xenopus laevis, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
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Andere Bezeichnung
- COPS2
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Hintergrund
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Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
Aliases: ALIEN antibody, Alien Drosophila himolog of antibody, Alien homolog antibody, COP 9 antibody, COP9 antibody, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody, COP9 constitutive photomorphogenic homolog subunit 2 antibody, COP9 signalosome complex subunit 2 antibody, COPS 2 antibody, Cops2 antibody, CSN2 antibody, CSN2_HUMAN antibody, JAB1 containing signalosome subunit 2 antibody, JAB1-containing signalosome subunit 2 antibody, SGN 2 antibody, SGN2 antibody, Signalosome subunit 2 antibody, Thyroid Hormone Receptor Interactor15 antibody, Thyroid Hormone Receptor Interactor 15 antibody, Thyroid receptor-interacting protein 15 antibody, TR-interacting protein 15 antibody, TRIP 15 antibody, TRIP-15 antibody, TRIP15 antibody
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UniProt
- P61201
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Pathways
- Zellzyklus
Target
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