CLASP2 Antikörper (AA 226-381) (Biotin)

Produktnummer ABIN7147937

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CLASP2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CLASP2 Antikörper (AA 226-381) (Biotin) (ABIN7147937)

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLASP2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-CLASP2 Antikörper (Biotin)

Bindungsspezifität: AA 226-381

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CLIP-associating protein 2 protein (226-381AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Andere Bezeichnung: CLASP2

Hintergrund:

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Aliases: CLAP2_HUMAN antibody, CLASP 2 antibody, Clasp2 antibody, CLIP associating protein 2 antibody, CLIP-associating protein 2 antibody, Cytoplasmic linker associated protein 2 antibody, Cytoplasmic linker-associated protein 2 antibody, hOrbit2 antibody, KIAA0627 antibody, Multiple asters (Mast) like homolog 2 antibody, Protein Orbit homolog 2 antibody

UniProt: O75122

Pathways: Microtubule Dynamics, Maintenance of Protein Location