CEP63 Antikörper (AA 1-495)
Kurzübersicht für CEP63 Antikörper (AA 1-495) (ABIN7147411)
Target
Alle CEP63 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-495
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Centrosomal protein of 63 kDa protein (1-495AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CEP63 (Centrosomal Protein 63kDa (CEP63))
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Andere Bezeichnung
- CEP63
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Hintergrund
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Background: Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression.
Aliases: CEP63Centrosomal protein of 63 kDa antibody, Cep63 antibody
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UniProt
- Q96MT8
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Pathways
- M Phase
Target
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