CEP63 Antikörper

Produktnummer ABIN7112613

Produktdetails anti-CEP63 Antikörper

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: centrosomal protein 63kDa

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CEP63

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Andere Bezeichnung: CEP63 (CEP63 Produkte)

Synonyme: 4921501M07 antikoerper, AL450317.13gm1 antikoerper, AW107703 antikoerper, CD20R antikoerper, D9Mgc41 antikoerper, D9Mgc48e antikoerper, ET2 antikoerper, zgc:63548 antikoerper, Cep63-A antikoerper, Cep63-B antikoerper, Xcep63 antikoerper, centrosomal protein 63 antikoerper, centrosomal protein 63kDa antikoerper, centrosomal protein 63kDa L homeolog antikoerper, CEP63 antikoerper, SYO3AOP1_1060 antikoerper, Cep63 antikoerper, cep63 antikoerper, cep63.L antikoerper

Hintergrund: Synonyms: Background:Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152, however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).

Molekulargewicht: 57-75kd

Gen-ID: 80254

UniProt: Q96MT8

Pathways: M Phase