CENPJ Antikörper (AA 1082-1248) (FITC)

Produktnummer ABIN7147364

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch CENPJ in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CENPJ Antikörper (AA 1082-1248) (FITC) (ABIN7147364)

Target: CENPJ (Centromere Protein J (CENPJ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPJ Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-CENPJ Antikörper (FITC)

Bindungsspezifität: AA 1082-1248

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Centromere protein J protein (1082-1248AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CENPJ

Target: CENPJ (Centromere Protein J (CENPJ))

Andere Bezeichnung: CENPJ

Hintergrund:

Background: Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Aliases: BM032 antibody, CENP-J antibody, CENPJ antibody, CENPJ_HUMAN antibody, Centromere protein J antibody, Centrosomal P4.1-associated protein antibody, CPAP antibody, LAG-3-associated protein antibody, LAP antibody, LIP1 antibody, LYST interacting protein LIP1 antibody, LYST interacting protein LIP7 antibody, LYST-interacting protein 1 antibody, MCPH6 antibody, Sas 4 antibody, SASS4 antibody, SCKL4 antibody

UniProt: Q9HC77

Pathways: M Phase