CENPJ Antikörper (C-Term)

Produktnummer ABIN6257592

Produktdetails anti-CENPJ Antikörper

Target: CENPJ (Centromere Protein J (CENPJ))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: CENPJ Antibody detects endogenous levels of total CENPJ.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPJ, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CENPJ

Target: CENPJ (Centromere Protein J (CENPJ))

Andere Bezeichnung: CENPJ (CENPJ Produkte)

Synonyme: CENPJ antikoerper, fi46g11 antikoerper, wu:fi46g11 antikoerper, si:dkey-46k9.9 antikoerper, BM032 antikoerper, CENP-J antikoerper, CPAP antikoerper, LAP antikoerper, LIP1 antikoerper, MCPH6 antikoerper, SASS4 antikoerper, SCKL4 antikoerper, Sas-4 antikoerper, 4932437H03Rik antikoerper, Gm81 antikoerper, centromere protein J antikoerper, Cenpj antikoerper, CENPJ antikoerper, cenpj antikoerper

Hintergrund:

Description: Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Gene: CENPJ

Molekulargewicht: 149kDa

Gen-ID: 55835

UniProt: Q9HC77

Pathways: M Phase