CP110 Antikörper (AA 1-280)

Produktnummer ABIN7147359

Der Kaninchen Polyklonal Anti-CP110-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, CP110 in Proben von Human zu detektieren.

Kurzübersicht für CP110 Antikörper (AA 1-280) (ABIN7147359)

Target: CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CP110 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CP110 Antikörper

Bindungsspezifität: AA 1-280

Verwendungszweck: CCP110 Antibody

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CP110

Target: CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))

Andere Bezeichnung: CCP110

Hintergrund:

Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

Aliases: 110 kDa centrosomal protein antibody, CCP110 antibody, Centriolar coiled coil protein 110 kDa antibody, Centrosomal protein 110 kDa antibody, Centrosomal protein CP110 antibody, Centrosomal protein of 110 kDa antibody, Cep110 antibody, CP110 antibody, CP110_HUMAN antibody, DKFZp781G1416 antibody, FAN antibody, KIAA0419 antibody

UniProt: O43303

Pathways: M Phase