CD276 Antikörper (AA 29-200)

Produktnummer ABIN7147148

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD276 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD276 Antikörper (AA 29-200) (ABIN7147148)

Target: CD276

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: AA 29-200

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human CD276 antigen protein (29-200AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD276

Target: CD276

Andere Bezeichnung: CD276

Hintergrund:

Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Aliases: 4Ig B7 H3 antibody, 4Ig-B7-H3 antibody, AU016588 antibody, B7 H3 antibody, B7 homolog 3 antibody, B7-H3 antibody, B7H3 antibody, B7RP-2 antibody, CD_antigen=CD276 antibody, CD276 antibody, CD276 antigen antibody, CD276 Molecule antibody, CD276_HUMAN antibody, Costimulatory molecule antibody, Flags: Precursor antibody, PSEC0249 antibody, UNQ309/PRO352 antibody

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints