CATSPER2 Antikörper (AA 5-112) (Biotin)

Produktnummer ABIN7147032

Der Kaninchen Polyklonal Anti-CATSPER2-Antikörper wurde für ELISA validiert. Er ist geeignet, CATSPER2 in Proben von Human zu detektieren.

Kurzübersicht für CATSPER2 Antikörper (AA 5-112) (Biotin) (ABIN7147032)

Target: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CATSPER2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-CATSPER2 Antikörper (Biotin)

Bindungsspezifität: AA 5-112

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cation channel sperm-associated protein 2 protein (5-112AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CATSPER2

Target: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Andere Bezeichnung: CATSPER2

Hintergrund:

Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

Aliases: CATSPER2 antibody, Cation channel sperm-associated protein 2 antibody, CatSper2 antibody

UniProt: Q96P56