Calreticulin Antikörper (AA 18-415)

Produktnummer ABIN7146564

Der Kaninchen Polyklonal Anti-Calreticulin-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet, Calreticulin in Proben von Human zu detektieren.

Kurzübersicht für Calreticulin Antikörper (AA 18-415) (ABIN7146564)

Target: Calreticulin (CALR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calreticulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Calreticulin Antikörper

Bindungsspezifität: AA 18-415

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Calreticulin protein (18-415AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Calreticulin

Target: Calreticulin (CALR)

Andere Bezeichnung: CALR

Hintergrund:

Background: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

Aliases: Autoantigen RO antibody, CALR antibody, CALR protein antibody, CALR_HUMAN antibody, Calregulin antibody, Calreticulin antibody, cC1qR antibody, CRP55 antibody, CRT antibody, CRTC antibody, Endoplasmic reticulum resident protein 60 antibody, Epididymis secretory sperm binding protein Li 99n antibody, ERp60 antibody, FLJ26680 antibody, grp60 antibody, HACBP antibody, HEL S 99n antibody, RO antibody, Sicca syndrome antigen A (autoantigen Ro, calreticulin) antibody, Sicca syndrome antigen A antibody, SSA antibody

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response