DDX42 Antikörper (AA 519-819) (Biotin)

Produktnummer ABIN7144991

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DDX42 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DDX42 Antikörper (AA 519-819) (Biotin) (ABIN7144991)

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX42 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-DDX42 Antikörper (Biotin)

Bindungsspezifität: AA 519-819

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DDX42

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Andere Bezeichnung: DDX42

Hintergrund:

Background: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Aliases: DDX42ATP-dependent RNA helicase DDX42 antibody, EC 3.6.4.13 antibody, DEAD box protein 42 antibody, RNA helicase-like protein antibody, RHELP antibody, RNA helicase-related protein antibody, RNAHP antibody, SF3b DEAD box protein antibody, Splicing factor 3B-associated 125 kDa protein antibody, SF3b125 antibody

UniProt: Q86XP3