DDX42 Antikörper (C-Term)

Produktnummer ABIN6261256

Produktdetails anti-DDX42 Antikörper

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX42 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: DDX42 Antibody detects endogenous levels of total DDX42.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DDX42, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DDX42

Target: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Andere Bezeichnung: DDX42 (DDX42 Produkte)

Synonyme: im:7148194 antikoerper, si:dkey-15n1.10 antikoerper, zgc:111815 antikoerper, DDX42P antikoerper, RHELP antikoerper, RNAHP antikoerper, SF3b125 antikoerper, 1810047H21Rik antikoerper, AW319508 antikoerper, AW556242 antikoerper, B430002H05Rik antikoerper, DEAD (Asp-Glu-Ala-Asp) box helicase 42 antikoerper, DEAD-box helicase 42 antikoerper, DEAD-box helicase 42 L homeolog antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 antikoerper, ddx42 antikoerper, DDX42 antikoerper, Ddx42 antikoerper, ddx42.L antikoerper

Hintergrund:

Description: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Gene: DDX42

Molekulargewicht: 103 kDa

Gen-ID: 11325

UniProt: Q86XP3