ASIC3 Antikörper (AA 62-320)

Produktnummer ABIN7143004

Dieses Anti-ASIC3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ASIC3 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für ASIC3 Antikörper (AA 62-320) (ABIN7143004)

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ASIC3 Antikörper

Bindungsspezifität: AA 62-320

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Acid-sensing ion channel 3 protein (62-320AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Andere Bezeichnung: ASIC3

Hintergrund:

Background: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.

Aliases: ACCN 3 antibody, Accn3 antibody, ACCN3_HUMAN antibody, Acid sensing ion channel 3 antibody, Acid-sensing ion channel 3 antibody, Amiloride sensitive cation channel 3 antibody, Amiloride sensitive cation channel 3 testis antibody, Amiloride-sensitive cation channel 3 antibody, ASIC 3 antibody, ASIC3 antibody, DRASIC antibody, hASIC 3 antibody, hASIC3 antibody, hTNaC 1 antibody, hTNaC1 antibody, Modulatory subunit of ASIC 2a antibody, Modulatory subunit of ASIC2a antibody, Neuronal amiloride sensitive cation channel 3 antibody, Neuronal amiloride-sensitive cation channel 3 antibody, Proton gated cation channel subunit antibody, SLNAC 1 antibody, SLNAC1 antibody, Testis sodium channel 1 antibody, TNaC 1 antibody, TNaC1 antibody

UniProt: Q9UHC3