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ASIC3 Antikörper (N-Term)

ACCN3 Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776167
  • Target Alle ASIC3 (ACCN3) Antikörper anzeigen
    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
    Bindungsspezifität
    • 14
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein
    Wirt
    • 37
    • 3
    • 1
    Kaninchen
    Klonalität
    • 41
    Polyklonal
    Konjugat
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASIC3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 23
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL
    Homologie
    Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3
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  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 531 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))
    Andere Bezeichnung
    ACCN3 (ACCN3 Produkte)
    Synonyme
    ACCN3 antikoerper, Accn3 antikoerper, DRASIC antikoerper, SLNAC1 antikoerper, TNaC1 antikoerper, AW742291 antikoerper, TNAC1 antikoerper, amiloride-sensitive cation channel 3 antikoerper, acid sensing ion channel subunit 3 antikoerper, acid-sensing (proton-gated) ion channel 3 antikoerper, ACCN3 antikoerper, ASIC3 antikoerper, Asic3 antikoerper
    Hintergrund
    ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
    Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
    Protein Interaction Partner: ASIC3, LIN7B, GOPC, INADL, DLG4, MAGI1, ASIC2, STOM, CSNK2A1, PRKACA, STOML1,
    Protein Size: 531
    Molekulargewicht
    58 kDa
    Gen-ID
    9311
    NCBI Accession
    NM_004769, NP_004760
    UniProt
    Q9UHC3
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