PSMC6 Antikörper (Regulatory Subunit)

Produktnummer ABIN7142226

Der Kaninchen Polyklonal anti-PSMC6 Antikörper wird verwendet zum Nachweis von PSMC6 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für PSMC6 Antikörper (Regulatory Subunit) (ABIN7142226)

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PSMC6 Antikörper

Bindungsspezifität: AA 1-260, Regulatory Subunit

Verwendungszweck: PSMC6 Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human 26S proteasome regulatory subunit 10B protein (1-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PSMC6

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Andere Bezeichnung: PSMC6

Hintergrund:

Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Aliases: 26S protease regulatory subunit 10B antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome AAA-ATPase subunit RPT4 antibody, CADP44 antibody, P44 antibody, Proteasome 26S subunit ATPase 6 antibody, Proteasome subunit p42 antibody, PRS10_HUMAN antibody, PSMC6 antibody, Rpt4 antibody, SUG2 antibody

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway