PSMC6 Antikörper (C-Term)

Produktnummer ABIN2788038

Produktdetails anti-PSMC6 Antikörper

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GFNGADLRNV CTEAGMFAIR ADHDFVVQED FMKAVRKVAD SKKLESKLDY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMC6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 389 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMC6

Target: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Andere Bezeichnung: PSMC6 (PSMC6 Produkte)

Synonyme: DDBDRAFT_0186051 antikoerper, DDBDRAFT_0232968 antikoerper, DDB_0186051 antikoerper, DDB_0232968 antikoerper, fb20g04 antikoerper, wu:fb20g04 antikoerper, wu:fc85c10 antikoerper, cadp44 antikoerper, sug2 antikoerper, PSMC6 antikoerper, psmc6-a antikoerper, NV13405 antikoerper, CADP44 antikoerper, P44 antikoerper, SUG2 antikoerper, p42 antikoerper, 2300001E01Rik antikoerper, AI451058 antikoerper, 26S protease regulatory subunit S10B antikoerper, 26S proteasome regulatory subunit 10B antikoerper, proteasome 26S subunit, ATPase 6 antikoerper, proteasome 26S subunit, ATPase 6 L homeolog antikoerper, 26S protease regulatory subunit 10B antikoerper, proteasome 26S subunit, ATPase 6 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase, 6 antikoerper, ATEG_02903 antikoerper, HCAG_04181 antikoerper, LOC5565051 antikoerper, EDI_289460 antikoerper, CpipJ_CPIJ003334 antikoerper, EHI_194070 antikoerper, PTRG_02716 antikoerper, BDBG_01801 antikoerper, psmC6 antikoerper, MCYG_07206 antikoerper, PITG_00229 antikoerper, VDBG_04729 antikoerper, MGYG_04704 antikoerper, TERG_01608 antikoerper, DICPUDRAFT_97252 antikoerper, Tsp_02519 antikoerper, prs10 antikoerper, LOC100282100 antikoerper, Psmc6 antikoerper, psmc6 antikoerper, psmc6.L antikoerper, PSMC6 antikoerper, LOC693577 antikoerper, psmc6.S antikoerper, LOC100117671 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Alias Symbols: CADP44, MGC12520, P44, SUG2, p42
Protein Interaction Partner: SDCBP, CCDC146, CYB5R2, HUWE1, UBC, PSMD9, PSMC6, PSMC3, SUMO2, STAU1, PSMD14, MDM2, ABCF1, UBR4, ADRM1, TXNL1, AIMP1, AIMP2, RPS21, RPS15A, RPS12, RPS8, QARS, PSMD12, PSMD11, PSMD8, PSMD4, UCHL5, DYNC1LI1, PSMD3, PSMD2, PSMD1, PSMC5, PSMC2, PSMC1, PARK2,
Protein Size: 389

Molekulargewicht: 44 kDa

Gen-ID: 5706

NCBI Accession: NM_002806, NP_002797

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway