KIT Antikörper (pTyr936)

Produktnummer ABIN7139089

Der Kaninchen Polyklonal anti-KIT Antikörper (ABIN7139089) detektiert spezifisch KIT in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KIT Antikörper (pTyr936) (ABIN7139089)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-KIT Antikörper

Bindungsspezifität: pTyr936

Verwendungszweck: Phospho-KIT (Tyr936) Antibody

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 936 (H-I-Y(p)-S-N) derived from Human c-Kit.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: KIT

Hintergrund:

Background: This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)

Martin, F.H. et al. (1990) Cell 63, 203-11.
Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62.
Gommerman, J.L. et al. (1997) J Biol Chem 272, 30519-25.
Nocka, K. et al. (1990) EMBO J 9, 1805-13.

Aliases: C Kit antibody, c-Kit antibody, c-Kit Ligand antibody, CD117 antibody, Kit antibody, Kit Ligand antibody, KIT oncogene antibody, KIT proto oncogene receptor tyrosine kinase antibody, KIT_HUMAN antibody, Mast cell growth factor receptor antibody, Mast/stem cell growth factor receptor Kit antibody, MGF antibody, p145 c-kit antibody, PBT antibody, Piebald trait protein antibody, Proto oncogene c Kit antibody, Proto oncogene tyrosine protein kinase Kit antibody, Proto-oncogene c-Kit antibody, SCF Receptor antibody, SCFR antibody, soluble KIT variant 1 antibody, Steel Factor Receptor antibody, Stem cell factor receptor antibody, tyrosine protein kinase Kit antibody, Tyrosine-protein kinase Kit antibody, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity