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ROCK2 Antikörper (pTyr722)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ROCK2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7139057

Kurzübersicht für ROCK2 Antikörper (pTyr722) (ABIN7139057)

Target

Alle ROCK2 Antikörper anzeigen
ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reaktivität

  • 97
  • 55
  • 54
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 91
  • 8
  • 1
Kaninchen

Klonalität

  • 87
  • 13
Polyklonal

Konjugat

  • 55
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ROCK2 Antikörper ist unkonjugiert

Applikation

  • 82
  • 37
  • 27
  • 27
  • 24
  • 18
  • 17
  • 14
  • 11
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 15
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr722

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    Immunogen

    Peptide sequence around phosphorylation site of Tyrosine 722(K-I-Y(p)-E-S) derived from Human ROCK2.

    Isotyp

    IgG
  • Applikationshinweise

    WB:1:500-1:1000,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

    Andere Bezeichnung

    ROCK2

    Hintergrund

    Background: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus.

    Aliases: coiled-coil-containing protein kinase 2 antibody, KIAA0619 antibody, p164 ROCK 2 antibody, p164 ROCK-2 antibody, Rho associated coiled coil containing protein kinase 2 antibody, Rho associated protein kinase 2 antibody, Rho associated, coiled coil containing protein kinase II antibody, Rho kinase 2 antibody, Rho-associated antibody, Rho-associated protein kinase 2 antibody, ROCK 2 antibody, Rock II antibody, Rock2 antibody, ROCK2_HUMAN antibody, Rock2m antibody, ROK alpha antibody, ROKalpha antibody

    UniProt

    O75116

    Pathways

    Microtubule Dynamics, WNT Signalweg, Tube Formation
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