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EPH Receptor A4 Antikörper (pTyr596)

This anti-EPH Receptor A4 antibody (ABIN7139033) is a Rabbit Polyclonal antibody detecting EPH Receptor A4 in WB, ELISA. Suitable for Human.
Produktnummer ABIN7139033

Kurzübersicht für EPH Receptor A4 Antikörper (pTyr596) (ABIN7139033)

Target

Alle EPH Receptor A4 (EPHA4) Antikörper anzeigen
EPH Receptor A4 (EPHA4)

Reaktivität

  • 79
  • 36
  • 22
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 92
  • 8
  • 1
  • 1
Kaninchen

Klonalität

  • 89
  • 9
  • 2
Polyklonal

Konjugat

  • 50
  • 9
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EPH Receptor A4 Antikörper ist unkonjugiert

Applikation

  • 58
  • 47
  • 36
  • 15
  • 13
  • 13
  • 13
  • 11
  • 8
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 10
    • 10
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr596

    Kreuzreaktivität

    Human, Maus

    Aufreinigung

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    Immunogen

    Peptide sequence around phosphorylation site of tyrosine 596 (R-T-Y(p)-V-D) derived from Human EPHA4 .

    Isotyp

    IgG
  • Applikationshinweise

    WB:1:500-1:1000,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    EPH Receptor A4 (EPHA4)

    Andere Bezeichnung

    EPHA4

    Hintergrund

    Background:

    Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity.

    Rikova K., Cell 131:1190-1203(2007) [PubMed: 18083107].
    Richter M., J. Neurosci. 27:14205-14215(2007) [PubMed: 18094260].
    Fu W.Y., Nat. Neurosci. 10:67-76(2007) [PubMed: 17143272].

    Aliases: Cek 8 antibody, CEK8 antibody, EK8 antibody, eph receptor a4 antibody, EPH-like kinase 8 antibody, EPHA4 antibody, EPHA4_HUMAN antibody, Ephrin type-A receptor 4 antibody, HEK 8 antibody, hEK8 antibody, Receptor protein-tyrosine kinase HEK8 antibody, Sek 1 antibody, SEK antibody, TYRO 1 protein tyrosine kinase antibody, TYRO1 antibody, Tyrosine-protein kinase receptor SEK antibody, Tyrosine-protein kinase TYRO1 antibody

    UniProt

    P54764

    Pathways

    RTK Signalweg
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