ENOS Antikörper (pSer615)

Produktnummer ABIN7138659

Der Kaninchen Polyklonal anti-ENOS Antikörper wird verwendet zum Nachweis von ENOS in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für ENOS Antikörper (pSer615) (ABIN7138659)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ENOS Antikörper

Bindungsspezifität: pSer615

Verwendungszweck: Phospho-NOS3 (Ser615) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 615 (F-N-S(p)-I-S) derived from Human eNOS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3

Hintergrund:

Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

Aliases: cNOS antibody, Constitutive NOS antibody, EC NOS antibody, EC-NOS antibody, ecNOS antibody, Endothelial nitric oxidase synthase antibody, Endothelial nitric oxide synthase antibody, Endothelial nitric oxide synthase 3 antibody, Endothelial NOS antibody, eNOS antibody, Nitric oxide synthase 3 (endothelial cell) antibody, Nitric oxide synthase 3 antibody, Nitric oxide synthase 3 endothelial cell antibody, Nitric oxide synthase endothelial antibody, Nitric oxide synthase, endothelial antibody, NOS 3 antibody, NOS III antibody, NOS type III antibody, NOS3 antibody, NOS3_HUMAN antibody, NOSIII antibody

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling