Retinoblastoma 1 Antikörper (pSer608)
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- Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
- Retinoblastoma 1 (RB1)
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Bindungsspezifität
- pSer608
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma.
- Isotyp
- IgG
- Top Product
- Discover our top product RB1 Primärantikörper
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- Applikationshinweise
- WB:1:500-1:1000, IHC:1:50-1:100,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Retinoblastoma 1 (RB1)
- Andere Bezeichnung
- RB1 (RB1 Produkte)
- Hintergrund
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Background:
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Lee W.-H., Nature 329:642-645(1987).
Lee W.-H., Science 235:1394-1399(1987).
Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).Aliases: Exon 17 tumor GOS561 substitution mutation causes premature stop antibody, GOS563 exon 17 substitution mutation causes premature stop antibody, OSRC antibody, Osteosarcoma antibody, p105-Rb antibody, P105RB antibody, PP105 antibody, pp110 antibody, PPP1R130 antibody, pRb antibody, Prepro retinoblastoma associated protein antibody, Protein phosphatase 1 regulatory subunit 130 antibody, Rb antibody, RB transcriptional corepressor 1 antibody, RB_HUMAN antibody, RB1 antibody, RB1 gene antibody, Retinoblastoma 1 antibody, Retinoblastoma suspectibility protein antibody, Retinoblastoma-associated protein antibody
- UniProt
- P06400
- Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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