CTNNB1 Antikörper (pSer37)

Produktnummer ABIN7138578

Der Kaninchen Polyklonal anti-CTNNB1 Antikörper wird verwendet zum Nachweis von CTNNB1 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für CTNNB1 Antikörper (pSer37) (ABIN7138578)

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTNNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CTNNB1 Antikörper

Bindungsspezifität: pSer37

Verwendungszweck: Phospho-CTNNB1 (Ser37) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 37 (I-H-S(p)-G-A) derived from Human b-Catenin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CTNNB1

Target: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Andere Bezeichnung: CTNNB1

Hintergrund:

Background: Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

Novak A, et al. (1998) Proc Natl Acad Sci U S A, 95(8): 4374-4379
Marin O, et al. (2003) Proc Natl Acad Sci U S A, 100(18): 10193-10200
Okamura H, et al. (2004) Mol Cell Biol, 24(10): 4184-4195
Xing Y, et al. (2003) Genes Dev, 17(22): 2753-2764
Barth AI, et al. (1999) Proc Natl Acad Sci U S A, 96(9): 4947-4952

Aliases: b-catenin antibody, Beta catenin antibody, Beta-catenin antibody, Cadherin associated protein antibody, Catenin (cadherin associated protein), beta 1, 88 kDa antibody, Catenin beta 1 antibody, Catenin beta-1 antibody, CATNB antibody, CHBCAT antibody, CTNB1_HUMAN antibody, CTNNB antibody, CTNNB1 antibody, DKFZp686D02253 antibody, FLJ25606 antibody, FLJ37923 antibody, OTTHUMP00000162082 antibody, OTTHUMP00000165222 antibody, OTTHUMP00000165223 antibody, OTTHUMP00000209288 antibody, OTTHUMP00000209289 antibody

UniProt: P35222

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2