CCR5 Antikörper (pSer349)

Produktnummer ABIN7138569

Produktdetails anti-CCR5 Antikörper

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Bindungsspezifität: pSer349

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Andere Bezeichnung: CCR5 (CCR5 Produkte)

Synonyme: CC-CKR-5 antikoerper, CCCKR5 antikoerper, CCR-5 antikoerper, CD195 antikoerper, CKR-5 antikoerper, CKR5 antikoerper, CMKBR5 antikoerper, IDDM22 antikoerper, Ckr5 antikoerper, Cmkbr5 antikoerper, CCR1-L antikoerper, GPCR antikoerper, CCR5 antikoerper, AM4-7 antikoerper, C-C motif chemokine receptor 5 (gene/pseudogene) antikoerper, chemokine (C-C motif) receptor 5 antikoerper, C-C motif chemokine receptor 5 antikoerper, CCR5 antikoerper, Ccr5 antikoerper

Hintergrund:

Background:

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Martin Oppermann, J. Biol. Chem., Mar 1999, 274: 8875.
Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003, 278: 2190 - 2198.
Ramtin Rahbar, J. Virol., Jul 2006, 80: 7245 - 7259.
H Olbrich, J. Leukoc. Biol., Mar 1999, 65: 281.

Aliases: AM4 7 antibody, C C chemokine receptor type 5 antibody, C C CKR 5 antibody, C-C chemokine receptor type 5 antibody, C-C CKR-5 antibody, C-C motif chemokine receptor 5 A159A antibody, CC Chemokine Receptor 5 antibody, CC Chemokine Receptor Type 5 antibody, CC CKR 5 antibody, CC-CKR-5 antibody, CCCKR 5 antibody, CCCKR5 antibody, CCR 5 antibody, CCR-5 antibody, CCR5 antibody, CCR5 chemokine (C C motif) receptor 5 antibody, CCR5_HUMAN antibody, CD 195 antibody, CD195 antibody, CD195 Antigen antibody, Chemokine C C motif receptor 5 antibody, Chemokine receptor CCR5 antibody, CHEMR13 antibody, CKR 5 antibody, CKR5 antibody, CMKBR 5 antibody, CMKBR5 antibody, FLJ78003 antibody, HIV 1 Fusion Coreceptor antibody, HIV-1 fusion coreceptor antibody, HIV1 fusion coreceptor antibody, IDDM22 antibody, MIP-1 alpha receptor antibody

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size