Cytokeratin 18 Antikörper (pSer33)

Produktnummer ABIN7138559

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cytokeratin 18 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cytokeratin 18 Antikörper (pSer33) (ABIN7138559)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Cytokeratin 18 Antikörper

Bindungsspezifität: pSer33

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 33 (A-A-S(p)-V-Y) derived from Human Keratin 18 (CK18).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: KRT18

Hintergrund:

Background: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. utations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Ramaekers, F.C. and Bosman, F.T. (2004) J. Pathol. 204, 351-354.
Chang, L. and Goldman, R.D. (2004) Nat. Rev. Mol. Cell Biol. 5, 601-613.
Moll, R. et al. (1982) Cell 31, 11-24.

Aliases: Cell proliferation inducing gene 46 protein antibody, Cell proliferation inducing protein 46 antibody, Cell proliferation-inducing gene 46 protein antibody, CK 18 antibody, CK-18 antibody, CK18 antibody, CYK 18 antibody, CYK18 antibody, Cytokeratin 18 antibody, Cytokeratin endo B antibody, Cytokeratin-18 antibody, K 18 antibody, K18 antibody, K1C18_HUMAN antibody, KA18 antibody, Keratin 18 antibody, Keratin 18, type I antibody, Keratin D antibody, keratin, type I cytoskeletal 18 antibody, Keratin-18 antibody, Krt18 antibody

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose