Cholesterol Esterase Antikörper (AA 151-180)

Produktnummer ABIN708806

Der Kaninchen Polyklonal Anti-Cholesterol Esterase-Antikörper wurde für WB, ELISA, IHC (fro), IF (cc), IF (p) und IHC (p) validiert. Er ist geeignet, Cholesterol Esterase in Proben von Human zu detektieren.

Kurzübersicht für Cholesterol Esterase Antikörper (AA 151-180) (ABIN708806)

Target: Cholesterol Esterase (CEL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cholesterol Esterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cholesterol Esterase Antikörper

Bindungsspezifität: AA 151-180

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bile salt-activated lipase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Cholesterol Esterase

Target: Cholesterol Esterase (CEL)

Andere Bezeichnung: Bile salt-activated lipase

Hintergrund:

Synonyms: BAL, Bile salt-stimulated lipase, BSDL, BSSL, Bucelipase, Carboxyl ester lipase bile salt stimulated lipase, Carboxyl ester lipase, CEase, CEL, CELL, Cholesterol esterase, FAP, FAPP, Fetoacinar pancreatic protein, LIPA, Lysophospholipase, pancreatic, MODY8. Pancreatic lysophospholipase, Sterol esterase antibody, CEL_HUMAN.

Background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat(VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq].

Gen-ID: 1056

Pathways: Lipid Metabolism