Cholesterol Esterase Antikörper (AA 454-482)

Produktnummer ABIN656486

Der Kaninchen Polyklonal anti-Cholesterol Esterase Antikörper wird verwendet zum Nachweis von Cholesterol Esterase in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Cholesterol Esterase Antikörper (AA 454-482) (ABIN656486)

Target: Cholesterol Esterase (CEL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cholesterol Esterase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB31034

Produktdetails anti-Cholesterol Esterase Antikörper

Bindungsspezifität: AA 454-482

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the Central region of human CEL.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Cholesterol Esterase

Target: Cholesterol Esterase (CEL)

Andere Bezeichnung: CEL

Hintergrund: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.

Molekulargewicht: 79322

UniProt: P19835

Pathways: Lipid Metabolism